Melatonin (LEF-330)

Melatonin (LEF-330)

$5.40

Melatonin - 3 mg, 60 capsules

Quantity:

Melatonin releases from the pineal gland, reaching its peak at night to help maintain tissues in a youthful state of health. Secretion of melatonin declines significantly with age, as the pineal gland becomes calcified.37,38

Melatonin keeps our circadian cycle in tune as it communicates with the body’s cells.39,40 Not only does this hormone work to maintain cell health, it appears to regulate a system of self-repair and regeneration.41,42 When this hard-working hormone is diminished, our biological functions are impaired.43,44

Many people use melatonin to help improve sleep. Some research has found that melatonin increases the speed of falling asleep and adds to the quality of sleep in about 60% of people who use it.45-47

References:

1. J Clin Endocrinol Metab. 1997 Aug;82(8):2396-402. http://jcem.endojournals.org/cgi/content/full/82/8/2396
2. J Immunol. 2002 Feb 15;168(4):1753-8.
3. J Endocrinol Invest. 2002 Jan;25(1):73-83.
4. J Clin Endocrinol Metab. 2000 Dec;85(12):4650-6.
5. Biol Psychiatry. 1999 Jun 15;45(12):1533-41.
6. Calcif Tissue Int. 2002 Mar;70(3):137-45. Epub 2002 Jan 31.
7. J Med Assoc Thai. 2001 Oct;84 Suppl 2:S605-12.
8. J Clin Encodrinol Metab. 1992 Oct;75(4):1002-4
9. J Endocrinol. 1999 Oct;163(1):1-5.
10. Biochem Pharmacol. 1995 Jan 6;49(1):1-16.
11. Proc Natl Acad Sci USA. 1992 Mar 1;89(5):1567-71.
12. Horm Metab Res. 1998 Jan;30(1):16-28. Review.
13. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):12308-12.
14. Menopause. 2004 May-Jun;11(3):246-54.
15. Menopause. 2000 Jul-Aug;7(4):215-29.
16. Menopause. 1998 Spring;5(1):9-15.
17. Menopause. 2003 May-Jun;10(3):196-202.
18. Nutr Clin Care. 2002 Nov-Dec;5(6):272-82.
19. Maturitas. 2003 Mar 14;44 Suppl 1:S21-9.
20. J Clin Endocrinol Metab. 2003 Sep;88(9):4077-9. Comment in: J Clin Endocrinol Metab. 2003 Sep;88(9):4075-6.
21. J Steroid Biochem Mol Biol. 2001 Sep;78(3):291-8.
22. Cancer Res. 2000 Oct 15;60(20):5704-9.
23. Obstet Gynecol. 2001 Jun;97(6):Suppl 1-11.
24. J Am Pharm Assoc. (Wash) 2000;40:234-42 http://www.medscape.com/viewarticle/406683
25. Hum Psychopharmacol. 2003 Apr;18(3):191-5.
26. Breast. 1999 Aug;8(4):175-181.
27. J Womens Health Gend Based Med. 2000 Apr;9(3):315-20.
28. Phytomedicine. 2003 May;10(4):348-57.
29. Phytomedicine. 2003 May;10(4):348-57.
30. Wien Med Wochenschr. 2002;152(15-16):364-72. [Article in German]
31. Horm Metab Res. 1993 May;25(5):253-5.
32. Menopause. 2003 Jan-Feb;10(1):13-8.
33. Obstet Gynecol. 1999 Aug;94(2):225-8.
34. Med Hypotheses. 1991 Aug;35(4):316-8.
Erratum in: Med Hypotheses. 1991 Oct;36(2):178.
35. Int Clin Nutr Rev. 1990;10:384-91.
36. Am J Obstet Gynecol. 1987;156:61-5.
37. Exp Gerontol. 2001 Jul;36(7):1083-100.
38. J Pineal Res. 1994 May;16(4):178-83.
39. Free Radic Res. 2002 Dec;36(12):1323-9.
40. J Endocrinol. 1981 Dec;91(3):467-75.
41. Surg Today. 2003;33(12):896-901.
42. Cytobios. 1996;85(340):51-8.
43. Maturitas. 2002 Apr 15;41 Suppl 1:S85-104.
44. Chronobiol Int. 2000 May;17(3):419-32.
45. Sleep. 1996 Jun;19(5):423-31.
46. Clin Pharmacol Ther. 1995 May;57(5):552-8.
47. Actas Esp Psiquiatr. 2000 Sep-Oct;28(5):325-9. [Article in Spanish]
48. N Engl J Med. 1990 Jul 5;323(1):1-6.
49. J Clin Invest. 1981 May;67(5):1361-9.
51. J Sports Med Phys Fitness. 1988 Mar;28(1):35-9.
52. Curr Med Res Opin. 1981;7(7):475-81.
53. Am J Clin Nutr. 1995 May;61(5):1058-61.
54. Acta Endocrinol (Copenh). 1980 Mar;93(3):283-6.
55. Metabolism. 1978 Feb;27(2):201-8.
56. Psychoneuroendocrinology. 1996 Apr;21(3):313-22.
57. Proc Natl Acad Sci USA. 1986 Aug;83(15):5663-7.
58. Fertil Steril. 1996 Aug;66(2):230-4.
59: Curr Therap Res. 2000;61(7):435-42.

Supplement Facts

Serving Size 1 capsule
Servings Per Container 60
Amount Per Serving
Melatonin	3 mg
Other ingredients: rice flour, gelatin, water.
Contains rice. This product contains NO milk, egg, fish, peanuts, crustacean shellfish, soybeans, tree nuts, wheat, yeast, gluten, or corn. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Dosage and Use

	Take one capsule 30 to 60 minutes before bedtime, or as recommended by a healthcare practitioner.
	Melatonin is naturally secreted from the pineal gland at night, and should be taken at night for optimal results.

Caution

If you have asthma or an autoimmune disease, do not use melatonin.

Attention Australia and New Zealand Customers

For all melatonin orders, please contact our authorized Fiji distributor at forlongerlife@connect.com.fj directly.

Warnings

None of the statements on this website have been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. Research is ongoing.

The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any medication without first consulting your physician.